Progynova is a brand name for a medication containing estradiol, which is a form of the hormone estrogen. It is commonly used in hormone replacement therapy (HRT) for transgender women and menopausal women to alleviate symptoms such as hot flashes, vaginal dryness, and mood swings. Progynova tablets come in various strengths, and the dosage prescribed depends on the individual's specific medical needs and hormone levels. It's important to use this medication under the guidance of a healthcare professional, as improper use can lead to adverse effects. Common side effects may include nausea, breast tenderness, and headaches. As with any medication, it's essential to discuss potential risks and benefits with a healthcare provider before starting treatment.